Acyclovir-d4 , CAS No.1185179-33-2

Item Number

A647325

Grouped product items
SKU	Size	Availability	Price	Qty
A647325-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$395.90
A647325-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,683.90

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Basic Description

Specifications & Purity	≥98%(CP),≥98 atom% D
Biochemical and Physiological Mechanisms	Acyclovir-d 4 is the deuterium labeled Acyclovir. Acyclovir (Aciclovir) is a guanosine analogue and an orally active antiviral agent. Acyclovir inhibits HSV-1 (IC50 of 0.85 μM), HSV-2 (IC50 of 0.86 μM) and varicella-zoster virus. Acyclovir can be phosphor
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	Acyclovir-d4 is the deuterium labeled Acyclovir. Acyclovir (Aciclovir) is a guanosine analogue and an orally active antiviral agent. Acyclovir inhibits HSV-1 (IC50 of 0.85 μM), HSV-2 (IC50 of 0.86 μM) and varicella-zoster virus. Acyclovir can be phosphorylated by viral thymidine kinase (TK), and Acyclovir triphosphate interferes with viral DNA polymerization through competitive inhibition with guanosine triphosphate and obligatory chain termination . Acyclovir prevents bacterial infections during induction therapy for acute leukaemia.

Names and Identifiers

IUPAC Name	2-amino-9-[(1,1,2,2-tetradeuterio-2-hydroxyethoxy)methyl]-1H-purin-6-one
INCHI	InChI=1S/C8H11N5O3/c9-8-11-6-5(7(15)12-8)10-3-13(6)4-16-2-1-14/h3,14H,1-2,4H2,(H3,9,11,12,15)/i1D2,2D2
InChi Key	MKUXAQIIEYXACX-LNLMKGTHSA-N
Canonical SMILES	C1=NC2=C(N1COCCO)N=C(NC2=O)N
Alternate CAS	59277-89-3（unlabelled）
Molecular Weight	229.23

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Basic Description