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9-cis-Retinoic Acid - 95%, high purity , CAS No.5300-03-8, Agonist of Retinoic acid receptor-α;Agonist of Retinoic acid receptor-β;Agonist of Retinoic acid receptor-γ;Agonist of Retinoid X receptor-α;Agonist of Retinoid X receptor-β;Agonist of Retinoid X receptor-γ

1 Citations
Item Number
C305934
Grouped product items
SKUSizeAvailabilityPrice Qty
C305934-1mg
1mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$35.90
C305934-5mg
5mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$147.90
C305934-10mg
10mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$246.90
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Metabolic Enzyme/Protease (0) RAR/RXR (0) Vitamin D Related/Nuclear Receptor (0)

Basic Description

SynonymsIsotretinoin Retinoic acid | Toctino | (2E,4E,6Z,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)nona-2,4,6,8-tetraenoic acid | [3H]-9-cis-retinoic acid | [3H]9-cis-retinoic acid | 1UA8E65KDZ | LG100057 | LG-100057 | tretinoine (French) (EINECS) | (2E,
Specifications & PurityMoligand™, ≥95%
Storage TempArgon charged,Store at -80°C
Shipped InIce chest + Ice pads
GradeMoligand™
Action TypeAGONIST
Mechanism of actionAgonist of Retinoic acid receptor-α;Agonist of Retinoic acid receptor-β;Agonist of Retinoic acid receptor-γ;Agonist of Retinoid X receptor-α;Agonist of Retinoid X receptor-β;Agonist of Retinoid X receptor-γ
Product Description

9-cis-Retinoic acid is a vitamin A analog that inhibits cell proliferation and induces cell differentiation. 9-cis-Retinoic acid is an inhibitor of Cox-2 and an activator of RAR α, RAR β, RAR γ and RXR.
A Cox-2 inhibitor that prevents cell proliferation and induces cell differentiation

AI Insight

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name (2E,4E,6Z,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenoic acid
INCHI InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8-,16-14+
InChi Key SHGAZHPCJJPHSC-ZVCIMWCZSA-N
Canonical SMILES CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC(=O)O)C)C
Isomeric SMILES CC1=C(C(CCC1)(C)C)/C=C/C(=C\C=C\C(=C\C(=O)O)\C)/C
WGK Germany 3
Alternate CAS 5300-03-8
PubChem CID 449171
NSC Number 659772
MeSH Entry Terms 9 cis Retinoic Acid;9-cis-retinoic acid;9cRA compound;alitretinoin;BAL4079;Panretin;Toctino
Molecular Weight 300.435

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

5 results found

Lot NumberCertificate TypeDateItem
C2513292Certificate of AnalysisMar 17, 2025 C305934
I2224152Certificate of AnalysisJul 17, 2024 C305934
I2224170Certificate of AnalysisJul 17, 2024 C305934
I2224158Certificate of AnalysisJul 02, 2024 C305934
A2107272Certificate of AnalysisOct 20, 2022 C305934

Safety and Hazards(GHS)

Pictogram(s) GHS08,   GHS07
Signal Danger
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

H360:May damage fertility or the unborn child

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P203:Obtain, read and follow all safety instructions before use.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P318:if exposed or concerned, get medical advice.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 3

Related Documents

 SDS

 Specification Sheet

FAQs and Articles

FAQ
Retinoic Acid and Gene Expression
Categories: Technical articles

Reviews

Customer Reviews

Citations of This Product

How to Cite Aladdin Scientific Products?
1. Mengying Wei, Yuanyuan Liu, Zifeng Pi, Kexin Yue, Shizhe Li, Mingxin Hu, Zhiqiang Liu, Fengrui Song, Zhongying Liu.  (2019)  Investigation of plasma metabolomics and neurotransmitter dysfunction in the process of Alzheimer's disease rat induced by amyloid beta 25-35.  RSC Advances,  9  (32): (18308-18319).  [PMID:35515227] [10.1039/C9RA00302A]

References

1. Mengying Wei, Yuanyuan Liu, Zifeng Pi, Kexin Yue, Shizhe Li, Mingxin Hu, Zhiqiang Liu, Fengrui Song, Zhongying Liu.  (2019)  Investigation of plasma metabolomics and neurotransmitter dysfunction in the process of Alzheimer's disease rat induced by amyloid beta 25-35.  RSC Advances,  9  (32): (18308-18319).  [PMID:35515227] [10.1039/C9RA00302A]

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