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6-Nitroso-1,2-benzopyrone , CAS No.130506-22-8
Basic Description Synonyms 6-nitroso-2H-chromen-2-one | 6-Nitrosocoumarin | NCGC00094193-01 | NCGC00261554-01 | Lopac0_000869 | SR-01000076033-1 | HMS3262N19 | SR-01000076033 | 6-Nitroso-1,2-benzopyrone | EU-0100869 | N 8403 | 6-nitrosochromen-2-one | DTXSID90156580 | SDCCGSBI-0050 Specifications & Purity ≥95% Storage Temp Store at -20°C,Argon charged Shipped In Ice chest + Ice pads Product Description 6-Nitroso-1,2-benzopyrone binds to the DNA-recognizing domain of ADP-ribosyltransferase and preferentially destabilizes one of the two zinc finger polypeptide complexes. The affected enzyme loses almost all activity, but still binds to DNA.
Mechanisms of Action Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References
Names and Identifiers Pubchem Sid 504750514 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/504750514 IUPAC Name 6-nitrosochromen-2-one INCHI InChI=1S/C9H5NO3/c11-9-4-1-6-5-7(10-12)2-3-8(6)13-9/h1-5H InChi Key HXTDAUGEZTYMGP-UHFFFAOYSA-N Canonical SMILES C1=CC2=C(C=CC(=O)O2)C=C1N=O Isomeric SMILES C1=CC2=C(C=CC(=O)O2)C=C1N=O PubChem CID 1871 Molecular Weight 175.14
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