6-Mercaptohexanoic acid - 95%, high purity , CAS No.17689-17-7

  • ≥95%
Item Number
M345400
Grouped product items
SKUSizeAvailabilityPrice Qty
M345400-250mg
250mg
4
$65.90
M345400-1g
1g
2
$200.90
M345400-5g
5g
3
$902.90

a thiol alkyl acid for the preparation of gold nanoparticles

Basic Description

Synonyms6-Mercaptohexanoic acid | 6-Mercapto-hexanoic acid | BDBM50404848 | J-011240 | CMNQZZPAVNBESS-UHFFFAOYSA-N | SCHEMBL173209 | F87188 | 5-carboxy-1-pentanethiol | DTXSID60317045 | AKOS006380117 | NSC310239 | NSC-310239 | EN300-1654205 | FT-0777852 | 6-sulfa
Specifications & Purity≥95%
Storage TempStore at -20°C,Argon charged
Shipped InIce chest + Ice pads
Product Description

Product Describtion:

6-Mercaptohexanoic acid is a hexane substituted with a carboxylic acid and a thiol at the termini. 6-Mercaptohexanoic acid is useful in the preparation of functionalized gold nanoparticles and hydrophilic self-assembled monolayers (SAMs) associated with gold substrates. 6-Mercaptohexanoic acid may also be a useful fragment for synthesis.


Product Application: MHA can be used in the surface modification of InP quantum nanowires for their potential uage in fluorescent chemical sensors that monitor cyanide ions. MHA may also be covalently bonded with liposomes that can form a SAM on the surface of gold for use as an insect odorant receptor in biosensor based applications. Used to prepare thiol-functionalized 1.5 nm gold nanoparticles via a ligand exchange process with triphenylphosphine-stabilized nanoparticles. This compound is used in self-assembly to produce hydrophilic SAMs. The resulting monolayers which are terminated with carboxylic acids can be further functionalized with various amines and alcohols to introduce more complex end groups. Can also be used to control the rate of aggregation of gold colloidal nanoparticles using pH.

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Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

Pubchem Sid504758489
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504758489
IUPAC Name 6-sulfanylhexanoic acid
INCHI InChI=1S/C6H12O2S/c7-6(8)4-2-1-3-5-9/h9H,1-5H2,(H,7,8)
InChi Key CMNQZZPAVNBESS-UHFFFAOYSA-N
Canonical SMILES C(CCC(=O)O)CCS
Isomeric SMILES C(CCC(=O)O)CCS
PubChem CID 329113
UN Number 3334
Packing Group III
Molecular Weight 148.22

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

8 results found

Lot NumberCertificate TypeDateItem
A2410044Certificate of AnalysisOct 17, 2022 M345400
B2311786Certificate of AnalysisOct 17, 2022 M345400
B2311837Certificate of AnalysisOct 17, 2022 M345400
B2311858Certificate of AnalysisOct 17, 2022 M345400
C2211520Certificate of AnalysisJan 24, 2022 M345400
C2211521Certificate of AnalysisJan 24, 2022 M345400
C2211522Certificate of AnalysisJan 24, 2022 M345400
C2211538Certificate of AnalysisJan 24, 2022 M345400

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

Class 9

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Citations of This Product

1. Zesong Ruan, Chunlei Zhang, Tingwang Shi, Zhiyuan Luo, Yuna Zhang, Zanxia Cao, Rentai Huang, Yunfeng Chen, Daxiang Cui.  (2022)  Gold nanoclusters-loaded hydrogel formed by dimeric hydrogen bonds crosslinking: A novel strategy for multidrug-resistant bacteria-infected wound healing.  Materials Today Bio,  16  (100426).  [PMID:36133795] [10.1016/j.mtbio.2022.100426]
2. Chunlei Zhang, Guangyu Chu, Zesong Ruan, Ning Tang, Cunfeng Song, Qichao Li, Wenjie Zhou, Jiale Jin, Hossam Haick, Yunfeng Chen, Daxiang Cui.  (2022)  Biomimetic Self-Assembling Metal–Organic Architectures with Non-Iridescent Structural Coloration for Synergetic Antibacterial and Osteogenic Activity of Implants.  ACS Nano,  16  (10): (16584–16597).  [PMID:36001338] [10.1021/acsnano.2c06030]

References

1. Zesong Ruan, Chunlei Zhang, Tingwang Shi, Zhiyuan Luo, Yuna Zhang, Zanxia Cao, Rentai Huang, Yunfeng Chen, Daxiang Cui.  (2022)  Gold nanoclusters-loaded hydrogel formed by dimeric hydrogen bonds crosslinking: A novel strategy for multidrug-resistant bacteria-infected wound healing.  Materials Today Bio,  16  (100426).  [PMID:36133795] [10.1016/j.mtbio.2022.100426]
2. Chunlei Zhang, Guangyu Chu, Zesong Ruan, Ning Tang, Cunfeng Song, Qichao Li, Wenjie Zhou, Jiale Jin, Hossam Haick, Yunfeng Chen, Daxiang Cui.  (2022)  Biomimetic Self-Assembling Metal–Organic Architectures with Non-Iridescent Structural Coloration for Synergetic Antibacterial and Osteogenic Activity of Implants.  ACS Nano,  16  (10): (16584–16597).  [PMID:36001338] [10.1021/acsnano.2c06030]

Solution Calculators