| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| T124790-1g | 1g | 3 | $42.90 | |
| T124790-5g | 5g | 3 | $146.90 | |
| T124790-25g | 25g | 1 | $658.90 |
| Synonyms | 5-(Trifluoromethoxy)-2,3-indolinedione | BGN7HVV394 | PD182431 | 5-trifluoromethoxy isatin | J-010500 | 5-(Trifluoromethoxy)isatin | 5-(trifluoromethoxy)-isatin | T2774 | AC-24982 | SB34179 | 5-(Trifluoromethoxy)isatin, 98% | BDBM22816 | DNDI1416954 | AMY |
|---|---|
| Specifications & Purity | ≥98% |
| Shipped In | Normal |
| Product Description | Usually used as reactant for preparation of (fluorinated-indolinonylidene)-hydrazine-carbothioamides by condensation with thiosemicarbazides,oxindole derivatives as TAk1 kinase inhibitors,isatin thiosemicarbazones via condensation with thiosemicarbazones as herpes simplex virus (HSV) inhibitors,indolinon-spirothiazolidinones as selective inhibitors of Mycobacterium tuberculosis protein tyrosine phosphatase B,indolone acetamides as antiseizure agents.And also used as reactant for synthesis of ortho disubstituted biphenyls, 3-substituted 2-indolinone RET kinase inhibitors. |
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
| Pubchem Sid | 504760962 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504760962 |
| IUPAC Name | 5-(trifluoromethoxy)-1H-indole-2,3-dione |
| INCHI | InChI=1S/C9H4F3NO3/c10-9(11,12)16-4-1-2-6-5(3-4)7(14)8(15)13-6/h1-3H,(H,13,14,15) |
| InChi Key | XHAJMVPMNOBILF-UHFFFAOYSA-N |
| Canonical SMILES | C1=CC2=C(C=C1OC(F)(F)F)C(=O)C(=O)N2 |
| Isomeric SMILES | C1=CC2=C(C=C1OC(F)(F)F)C(=O)C(=O)N2 |
| WGK Germany | 3 |
| PubChem CID | 2732752 |
| Molecular Weight | 231.13 |
| Reaxy-Rn | 8690030 |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 B1625043 | Certificate of Analysis | Oct 08, 2023 | T124790 |
| I2304540 | Certificate of Analysis | Aug 09, 2023 | T124790 |
| I2304541 | Certificate of Analysis | Aug 09, 2023 | T124790 |
| I2304542 | Certificate of Analysis | Aug 09, 2023 | T124790 |
| I2304543 | Certificate of Analysis | Aug 09, 2023 | T124790 |
| I2304566 | Certificate of Analysis | Aug 09, 2023 | T124790 |
| I2304567 | Certificate of Analysis | Aug 09, 2023 | T124790 |
| WGK Germany | 3 |
|---|---|
| Reaxy-Rn | 8690030 |
| 1. Cuiling Wang, Jiaxu Yan, Mo Du, Joseph A. Burlison, Chi Li, Yanni Sun, Danqing Zhao, Jianli Liu. (2017) One step synthesis of indirubins by reductive coupling of isatins with KBH4. TETRAHEDRON, 73 (2780). [PMID:] [10.1016/j.tet.2017.03.077] |
| 1. Cuiling Wang, Jiaxu Yan, Mo Du, Joseph A. Burlison, Chi Li, Yanni Sun, Danqing Zhao, Jianli Liu. (2017) One step synthesis of indirubins by reductive coupling of isatins with KBH4. TETRAHEDRON, 73 (2780). [PMID:] [10.1016/j.tet.2017.03.077] |
