| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| I655329-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $310.90 |
| Specifications & Purity | 10mM in DMSO |
|---|---|
| Biochemical and Physiological Mechanisms | 5-Iodo-indirubin-3'-monoxime is a potent GSK-3β , CDK5/P25 and CDK1/cyclin B inhibitor, competing with ATP for binding to the catalytic site of the kinase, with IC 50 s of 9, 20 and 25 nM, respectively. |
| Storage Temp | Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Product Description | 5-Iodo-indirubin-3'-monoxime is a potent GSK-3β , CDK5/P25 and CDK1/cyclin B inhibitor, competing with ATP for binding to the catalytic site of the kinase, with IC 50 s of 9, 20 and 25 nM, respectively IC50& Target:GSK-3β 9 nM (IC 50 ) Cdk5/p25 20 nM (IC 50 ) Cdk1/cyclin B 25 nM (IC 50 ) |
| Canonical SMILES | O/N=C(C1=CC=CC=C1N2)/C2=C3C(NC4=C/3C=C(I)C=C4)=O |
|---|---|
| Molecular Weight | 403.17 |
