| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| F420428-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $69.90 |
| Synonyms | 10356-76-0 | 2'-Deoxy-5-fluorocytidine | 5-FLUORO-2'-DEOXYCYTIDINE | FdCyd | 5-Fluorodeoxycytidine | FCdR | 4-amino-5-fluoro-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one | 5-Fluoro-2-deoxycytidine | NSC-48006 | Cytidine, 2'-deoxy-5-fluo |
|---|---|
| Specifications & Purity | 10mM in DMSO |
| Biochemical and Physiological Mechanisms | 5-Fluoro-2′-deoxycytidine is a mechanism based DNMT (DNA cytosine-5 methyltransferase) inhibitor, that forms a covalent link with the cysteine residue in the active site of DNMT. |
| Storage Temp | Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
| IUPAC Name | 4-amino-5-fluoro-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one |
|---|---|
| INCHI | InChI=1S/C9H12FN3O4/c10-4-2-13(9(16)12-8(4)11)7-1-5(15)6(3-14)17-7/h2,5-7,14-15H,1,3H2,(H2,11,12,16)/t5-,6+,7+/m0/s1 |
| InChi Key | IDYKCXHJJGMAEV-RRKCRQDMSA-N |
| Canonical SMILES | C1C(C(OC1N2C=C(C(=NC2=O)N)F)CO)O |
| Isomeric SMILES | C1[C@@H]([C@H](O[C@H]1N2C=C(C(=NC2=O)N)F)CO)O |
| RTECS | HA3850000 |
| PubChem CID | 515328 |
| Molecular Weight | 245.21 |
| Reaxy-Rn | 619209 |
| Pictogram(s) | GHS07 |
|---|---|
| Signal | Warning |
| Hazard Statements | H302:Harmful if swallowed |
| Precautionary Statements | P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P317:IF SWALLOWED: Get medical help. |
| RTECS | HA3850000 |
| Reaxy-Rn | 619209 |
