| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| E156345-50mg | 50mg | 2 | $192.90 | |
| E156345-200mg | 200mg | 2 | $573.90 |
DNA synthesis monitoring probe
| Synonyms | AS-59861 | CS-0108176 | AKOS027253006 | Cytidine, 2'-deoxy-5-ethynyl- | D90593 | A900532 | MFCD22417249 | 5-Ethynyl-2'-deoxycytidine, (EdC), AldrichCPR | 5-Ethynyl-2'-deoxycytidine | SCHEMBL6906161 | DTXSID10567311 | 4-amino-5-ethynyl-1-[(2R,4S,5R)-4-hydr |
|---|---|
| Specifications & Purity | ≥98%(N) |
| Biochemical and Physiological Mechanisms | Relatively nontoxic 2’-deoxycytidine analog. Alternative to BrdU (5-Bromo-2’-deoxyuridine) for measuring de novo DNA synthesis during S-phase. Incorporates into replicating DNA instead of its natural analog thymidine. |
| Shipped In | Normal |
| Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
| Pubchem Sid | 504767759 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504767759 |
| IUPAC Name | 4-amino-5-ethynyl-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one |
| INCHI | InChI=1S/C11H13N3O4/c1-2-6-4-14(11(17)13-10(6)12)9-3-7(16)8(5-15)18-9/h1,4,7-9,15-16H,3,5H2,(H2,12,13,17)/t7-,8+,9+/m0/s1 |
| InChi Key | HMJSYXIPNSASJY-DJLDLDEBSA-N |
| Canonical SMILES | C#CC1=CN(C(=O)N=C1N)C2CC(C(O2)CO)O |
| Isomeric SMILES | C#CC1=CN(C(=O)N=C1N)[C@H]2C[C@@H]([C@H](O2)CO)O |
| WGK Germany | 3 |
| PubChem CID | 15036533 |
| Molecular Weight | 251.24 |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 J1923148 | Certificate of Analysis | Aug 04, 2023 | E156345 |
| WGK Germany | 3 |
|---|
| 1. Yuan-Jhe Chang,Marcus S Cooke,Chiung-Wen Hu,Mu-Rong Chao. (2018-06-27) Novel approach to integrated DNA adductomics for the assessment of in vitro and in vivo environmental exposures.. Archives of toxicology, 92 ((8)): (2665-2680). [PMID:29943112] |
| 2. Ramya Nandakumar,Roland Tschismarov,Felix Meissner,Thaneas Prabakaran,Abhichart Krissanaprasit,Ensieh Farahani,Bao-Cun Zhang,Sonia Assil,Amandine Martin,Wilhelm Bertrams,Christian K Holm,Andrea Ablasser,Tanja Klause,Martin K Thomsen,Bernd Schmeck,Kenneth A Howard,Thomas Henry,Kurt V Gothelf,Thomas Decker,Søren R Paludan. (2019-02-26) Intracellular bacteria engage a STING-TBK1-MVB12b pathway to enable paracrine cGAS-STING signalling.. Nature microbiology, 4 ((4)): (701-713). [PMID:30804548] |
| 3. Steven McFarlane,Anne Orr,Ashley P E Roberts,Kristen L Conn,Victor Iliev,Colin Loney,Ana da Silva Filipe,Katherine Smollett,Quan Gu,Neil Robertson,Peter D Adams,Taranjit Singh Rai,Chris Boutell. (2019-03-23) The histone chaperone HIRA promotes the induction of host innate immune defences in response to HSV-1 infection.. PLoS pathogens, 15 ((3)): (e1007667-e1007667). [PMID:30901352] |
