| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| A305285-100mg | 100mg | 10 | $32.90 | |
| A305285-250mg | 250mg | 2 | $68.90 | |
| A305285-1g | 1g | 3 | $210.90 | |
| A305285-5g | 5g | 2 | $947.90 |
| Synonyms | 5-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione | 191732-76-0 | 5-Aminothalidomide | 5-amino-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione | MFCD30188077 | 1H-Isoindole-1,3(2H)-dione, 5-amino-2-(2,6-dioxo-3-piperidinyl)- | 1,3-dioxo-2-(2,6-dioxopiperidin-3- |
|---|---|
| Specifications & Purity | ≥95% |
| Storage Temp | Store at 2-8°C,Argon charged |
| Shipped In | Wet ice |
| Product Description | Application： 5-Amino-Thalidomide is a derivative of the Cereblon (CRBN)-binding ligand thalidomide. 5-Amino-Thalidomide can be used to bind the CRBN E3 ubiquitin ligase in targeted protein degradation research or in the synthesis of protein degraders with a C5 exit vector. |
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
| Pubchem Sid | 488196326 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488196326 |
| IUPAC Name | 5-amino-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione |
| INCHI | InChI=1S/C13H11N3O4/c14-6-1-2-7-8(5-6)13(20)16(12(7)19)9-3-4-10(17)15-11(9)18/h1-2,5,9H,3-4,14H2,(H,15,17,18) |
| InChi Key | IICWMVJMJVXCLY-UHFFFAOYSA-N |
| Canonical SMILES | C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C=C(C=C3)N |
| Isomeric SMILES | C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C=C(C=C3)N |
| PubChem CID | 9816958 |
| Molecular Weight | 273.25 |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 D2126066 | Certificate of Analysis | Feb 06, 2024 | A305285 |
| D2126067 | Certificate of Analysis | Feb 06, 2024 | A305285 |
| A2329226 | Certificate of Analysis | Dec 05, 2022 | A305285 |
| A2329227 | Certificate of Analysis | Dec 05, 2022 | A305285 |
| A2329228 | Certificate of Analysis | Dec 05, 2022 | A305285 |
| A2329229 | Certificate of Analysis | Dec 05, 2022 | A305285 |
| Pictogram(s) | GHS07 |
|---|---|
| Signal | Warning |
| Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed H312:Harmful in contact with skin H332:Harmful if inhaled |
| Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P317:Get emergency medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
