5,7-Dichlorokynurenic acid - 97%, high purity , CAS No.131123-76-7, Antagonist of GluN1;Antagonist of GluN2A;Antagonist of GluN2B;Antagonist of GluN2C;Antagonist of GluN2D;Antagonist of glycine receptor α2 subunit

Item Number
D274816
Grouped product items
SKUSizeAvailabilityPrice Qty
D274816-10mg
10mg
5
$83.90
D274816-50mg
50mg
5
$310.90
D274816-100mg
100mg
5
$559.90
D274816-500mg
500mg
4
$2,519.90

NMDA receptor glycine site antagonist

Basic Description

SynonymsNCGC00015313-06 | Spectrum2_001999 | 5,7-dichlorokynurenic-acid | FT-0743570 | GTPL2361 | PDSP2_000182 | BSPBio_003412 | NCGC00015313-05 | NCGC00024525-04 | 5,7-Dichloro-4-hydroxy-quinoline-2-carboxylic acid(DCKA) | HMS3266E21 | Lopac-D-138 | AKOS01591382
Specifications & PurityMoligand™, ≥97%
Biochemical and Physiological MechanismsPotent NMDA receptor glycine site antagonist.
Storage TempStore at -20°C,Desiccated
Shipped InIce chest + Ice pads
GradeMoligand™
Action TypeANTAGONIST
Mechanism of actionAntagonist of GluN1;Antagonist of GluN2A;Antagonist of GluN2B;Antagonist of GluN2C;Antagonist of GluN2D;Antagonist of glycine receptor α2 subunit
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.

AI Insight

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

Pubchem Sid488179640
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488179640
IUPAC Name 5,7-dichloro-4-oxo-1H-quinoline-2-carboxylic acid
INCHI InChI=1S/C10H5Cl2NO3/c11-4-1-5(12)9-6(2-4)13-7(10(15)16)3-8(9)14/h1-3H,(H,13,14)(H,15,16)
InChi Key BGKFPRIGXAVYNX-UHFFFAOYSA-N
Canonical SMILES C1=C(C=C(C2=C1NC(=CC2=O)C(=O)O)Cl)Cl
Isomeric SMILES C1=C(C=C(C2=C1NC(=CC2=O)C(=O)O)Cl)Cl
Alternate CAS 131123-76-7,190908-40-8
PubChem CID 1779
MeSH Entry Terms 5,7-DCKA;5,7-dichlorokynurenic acid;5,7-dichloroquinurenic acid
Molecular Weight 258.06

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

8 results found

Lot NumberCertificate TypeDateItem
C2330624Certificate of AnalysisJan 15, 2024 D274816
C2330622Certificate of AnalysisJan 15, 2024 D274816
C2330621Certificate of AnalysisJan 15, 2024 D274816
C2330620Certificate of AnalysisJan 15, 2024 D274816
C2330613Certificate of AnalysisJan 12, 2024 D274816
C2330616Certificate of AnalysisJan 12, 2024 D274816
C2330619Certificate of AnalysisJan 12, 2024 D274816
C2330623Certificate of AnalysisJan 12, 2024 D274816

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

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