4-Hydroxyindole - 98%, high purity , CAS No.2380-94-1

  • ≥98%
Item Number
H105121
Grouped product items
SKUSizeAvailabilityPrice Qty
H105121-1g
1g
5
$15.90
H105121-5g
5g
4
$55.90
H105121-25g
25g
4
$203.90
H105121-100g
100g
2
$731.90

Basic Description

SynonymsSTK802156 | PS-3280 | Z1203730747 | 4-Indolol | NCGC00253639-01 | UNII-1W4VD9085V | EINECS 219-177-2 | 4-HYDROXYINDOLE [USP-RS] | 82CYO8A460 | Indol-4-ol | SR-01000944737-1 | AC-5462 | AM20060360 | SY001960 | 4-Hydroxyindole, 99% | CCG-214548 | SR-0100094
Specifications & Purity≥98%
Storage TempArgon charged
Shipped InNormal
Product Description

· Reactant for preparation of N-β-D-xylosyl-indole derivatives as SGLT2 inhibitors for management of hyperglycemia in diabetes · Reactant for preparation of small molecules targeting interaction between HIV-1 integrase and LEDGF/p75 cofactor · Reactant for preparation of dopamine D2 receptor antagonists · Reactant for preparation of SCD inhibitor MF-438 · Reactant for preparation of carbon-11-labeled 4-aryl-4H-chromenes as new PET agents for imaging of apoptosis in cancer · Reactant for preparation of indole/quinoline carbothioic acid amide derivatives as HCV inhibitors

AI Insight

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

Pubchem Sid488185099
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488185099
IUPAC Name 1H-indol-4-ol
INCHI InChI=1S/C8H7NO/c10-8-3-1-2-7-6(8)4-5-9-7/h1-5,9-10H
InChi Key NLMQHXUGJIAKTH-UHFFFAOYSA-N
Canonical SMILES C1=CC2=C(C=CN2)C(=C1)O
Isomeric SMILES C1=CC2=C(C=CN2)C(=C1)O
WGK Germany 3
PubChem CID 75421
Molecular Weight 133.15
Beilstein 114905
Reaxy-Rn 114905

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

8 results found

Lot NumberCertificate TypeDateItem
G2027101Certificate of AnalysisMay 08, 2024 H105121
D2428278Certificate of AnalysisMar 23, 2024 H105121
C1918158Certificate of AnalysisJan 15, 2023 H105121
J2226455Certificate of AnalysisSep 01, 2022 H105121
J2226456Certificate of AnalysisSep 01, 2022 H105121
J2226618Certificate of AnalysisSep 01, 2022 H105121
J2226708Certificate of AnalysisSep 01, 2022 H105121
E1816108Certificate of AnalysisApr 01, 2022 H105121

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 3
Reaxy-Rn 114905

Related Documents

Reviews

Customer Reviews

Citations of This Product

1. Longfei Zhang, Li Yang, Yewei Xu, Guanjun Chang.  (2019)  Renewable 4-HIF/NaOH aerogel for efficient methylene blue removal via cation–π interaction induced electrostatic interaction.  RSC Advances,  (51): (29772-29778).  [PMID:35531533] [10.1039/C9RA04166D]

References

1. Gavin Carr,Marco K W Chung,A Grant Mauk,Raymond J Andersen.  (2008-04-09)  Synthesis of indoleamine 2,3-dioxygenase inhibitory analogues of the sponge alkaloid exiguamine A..  Journal of medicinal chemistry,  51  ((9)): (2634-2637).  [PMID:18393489]
2. Monica Mazzarino,Xavier de la Torre,Francesco Botrè.  (2014-07-09)  A liquid chromatography-mass spectrometry method based on class characteristic fragmentation pathways to detect the class of indole-derivative synthetic cannabinoids in biological samples..  Analytica chimica acta,  837  (70-82).  [PMID:25000860]
3. Susana Sadler Simões,Inês Silva,Antonio Castañera Ajenjo,Mário João Dias.  (2014-08-16)  Validation and application of an UPLC-MS/MS method for the quantification of synthetic cannabinoids in urine samples and analysis of seized materials from the Portuguese market..  Forensic science international,  243  (117-125).  [PMID:25127518]
4. Bin Yang,Zhongjian Li,Lecheng Lei,Feifei Sun,Jingke Zhu.  (2015-10-23)  Prediction of Setschenow constants of N-heteroaromatics in NaCl solutions based on the partial charge on the heterocyclic nitrogen atom..  Environmental science and pollution research international,  23  ((4)): (3399-3405).  [PMID:26490915]
5. Martin Švidrnoch,Adam Přibylka,Vítězslav Maier.  (2016-02-04)  Determination of selected synthetic cannabinoids and their metabolites by micellar electrokinetic chromatography--mass spectrometry employing perfluoroheptanoic acid-based micellar phase..  Talanta,  150  (568-576).  [PMID:26838444]
6. Marek Bednarski,Monika Otto,Magdalena Dudek,Marcin Kołaczkowski,Adam Bucki,Agata Siwek,Grażyna Groszek,Elżbieta Maziarz,Piotr Wilk,Jacek Sapa.  (2016-02-09)  Synthesis and Pharmacological Activity of a New Series of 1-(1H-Indol-4-yloxy)-3-(2-(2-methoxyphenoxy)ethylamino)propan-2-ol Analogs..  Archiv der Pharmazie,  349  ((3)): (211-223).  [PMID:26853441]
7. Shalenie P den Braver-Sewradj,Michiel W den Braver,Audrey Baze,Joachim Decorde,Massimiliano Fonsi,Philippe Bachellier,Nico P E Vermeulen,Jan N M Commandeur,Lysiane Richert,J Chris Vos.  (2017-08-06)  Direct comparison of UDP-glucuronosyltransferase and cytochrome P450 activities in human liver microsomes, plated and suspended primary human hepatocytes from five liver donors..  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences,  109  (96-110).  [PMID:28778465]
8. Stefan W Toennes,Anna Geraths,Werner Pogoda,Alexander Paulke,Cora Wunder,Eef L Theunissen,Johannes G Ramaekers.  (2017-10-03)  Pharmacokinetic properties of the synthetic cannabinoid JWH-018 in oral fluid after inhalation..  Drug testing and analysis,  10  ((4)): (644-650).  [PMID:28967189]
9. Shalenie P den Braver-Sewradj,Michiel W den Braver,Marc van Dijk,Yongjie Zhang,Stefan J Dekker,Lukas Wijaya,Nico P E Vermeulen,Lysiane Richert,Jan N M Commandeur,J Chris Vos.  (2018-01-11)  Inter-individual Variability in Activity of the Major Drug Metabolizing Enzymes in Liver Homogenates of 20 Individuals..  Current drug metabolism,  19  ((4)): (370-381).  [PMID:29318967]
10. Alexandra M Adams,Nicholas A Kaplan,Zhangyue Wei,John D Brinton,Chantal S Monnier,Alexis L Enacopol,Theresa A Ramelot,J Andrew Jones.  (2019-09-25)  In vivo production of psilocybin in E. coli..  Metabolic engineering,  56  (111-119).  [PMID:31550507]
11. Nenad Manevski,Mika Kurkela,Camilla Höglund,Timo Mauriala,Michael H Court,Jari Yli-Kauhaluoma,Moshe Finel.  (2009-12-17)  Glucuronidation of psilocin and 4-hydroxyindole by the human UDP-glucuronosyltransferases..  Drug metabolism and disposition: the biological fate of chemicals,  38  ((3)): (386-395).  [PMID:20007669]
12. Stefan W Toennes,Anna Geraths,Werner Pogoda,Alexander Paulke,Cora Wunder,Eef L Theunissen,Johannes G Ramaekers.  (2017-04-04)  Pharmacokinetic properties of the synthetic cannabinoid JWH-018 and of its metabolites in serum after inhalation..  Journal of pharmaceutical and biomedical analysis,  140  (215-222).  [PMID:28365515]
13. Longfei Zhang, Li Yang, Yewei Xu, Guanjun Chang.  (2019)  Renewable 4-HIF/NaOH aerogel for efficient methylene blue removal via cation–π interaction induced electrostatic interaction.  RSC Advances,  (51): (29772-29778).  [PMID:35531533] [10.1039/C9RA04166D]

Solution Calculators