| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| A107207-1g | 1g | 5 | $9.90 | |
| A107207-5g | 5g | 5 | $34.90 | |
| A107207-25g | 25g | 4 | $114.90 | |
| A107207-100g | 100g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $410.90 |
PARP inhibitor
| Synonyms | CCG-39623 | BCP9000790 | CCRIS 3925 | 3-aminobenzamide | 3-Amino-benzamide | BSPBio_001432 | HMS3656P18 | KBio2_002355 | Spectrum5_001459 | BCBcMAP01_000186 | cMAP_000029 | UPCMLD-DP128:001 | BDBM27506 | KBio2_000152 | KBio2_004923 | KBioSS_000152 | SR-01 |
|---|---|
| Specifications & Purity | ≥98% |
| Biochemical and Physiological Mechanisms | INO-1001 a novel potent PARP inhibitor with an IC50 of 3 nM.Poly(ADP-ribose) polymerase (PARP) inhibitor (K i = 1.8 µM). Displays various biological actions including stimulation of angiogenesis. Additionally displays neuroprotective, anti-necrotic effect |
| Storage Temp | Argon charged |
| Shipped In | Normal |
| Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
| Product Description | 3-Aminobenzamide has been used as a poly-(ADP-ribose) polymerase (PARP) inhibitor in various experimental studies |
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
| Pubchem Sid | 488179631 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488179631 |
| IUPAC Name | 3-aminobenzamide |
| INCHI | InChI=1S/C7H8N2O/c8-6-3-1-2-5(4-6)7(9)10/h1-4H,8H2,(H2,9,10) |
| InChi Key | GSCPDZHWVNUUFI-UHFFFAOYSA-N |
| Canonical SMILES | C1=CC(=CC(=C1)N)C(=O)N |
| Isomeric SMILES | C1=CC(=CC(=C1)N)C(=O)N |
| WGK Germany | 3 |
| RTECS | CU8992000 |
| PubChem CID | 1645 |
| Molecular Weight | 136.15 |
| Beilstein | 14(3)998 |
| Reaxy-Rn | 2802373 |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 B1614010 | Certificate of Analysis | Oct 07, 2023 | A107207 |
| B2324400 | Certificate of Analysis | Mar 03, 2023 | A107207 |
| B2324388 | Certificate of Analysis | Mar 03, 2023 | A107207 |
| B2324402 | Certificate of Analysis | Mar 02, 2023 | A107207 |
| B2505135 | Certificate of Analysis | Aug 20, 2021 | A107207 |
| H2109144 | Certificate of Analysis | Aug 20, 2021 | A107207 |
| Pictogram(s) | GHS07 |
|---|---|
| Signal | Warning |
| Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed |
| Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
| WGK Germany | 3 |
| RTECS | CU8992000 |
| Reaxy-Rn | 2802373 |
| 1. Yuanyuan Xu, Li Liu, Zhaoyin Wang, Zhihui Dai. (2016) Stable and Reusable Electrochemical Biosensor for Poly(ADP-ribose) Polymerase and Its Inhibitor Based on Enzyme-Initiated Auto-PARylation. ACS Applied Materials & Interfaces, 8 (29): (18669–18674). [PMID:27367274] [10.1021/acsami.6b01883] |
| 1. Yuanyuan Xu, Li Liu, Zhaoyin Wang, Zhihui Dai. (2016) Stable and Reusable Electrochemical Biosensor for Poly(ADP-ribose) Polymerase and Its Inhibitor Based on Enzyme-Initiated Auto-PARylation. ACS Applied Materials & Interfaces, 8 (29): (18669–18674). [PMID:27367274] [10.1021/acsami.6b01883] |
