3,3'-Dipropylthiadicarbocyanine iodide - ≥98%, high purity , CAS No.53213-94-8

  • ≥98%
Item Number
D131515
Grouped product items
SKUSizeAvailabilityPrice Qty
D131515-25mg
25mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$23.90
D131515-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$48.90
D131515-100mg
100mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$76.90
D131515-250mg
250mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$132.90
D131515-1g
1g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$269.90

Fluorogenic probe for transmembrane potential measurements.

Basic Description

SynonymsDiSC3(5) | AKOS016010215 | HY-D0085 | 3-propyl-2-[(1E,3E)-5-[(2Z)-3-propyl-2,3-dihydro-1,3-benzothiazol-2-ylidene]penta-1,3-dien-1-yl]-1,3-benzothiazol-3-ium iodide | CS-0009996 | EN300-21687611
Specifications & Purity≥98%
Biochemical and Physiological MechanismsFluorogenic probe used to detect and measure changes in transmembrane potential or configuration induced by membrane altering agents.
Storage TempStore at -20°C,Argon charged
Shipped InIce chest + Ice pads
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

3,3'-Dipropylthiadicarbocyanine iodide is applied for transmembrane potential measurements.
Usually used as a fluorogenic probe to detect and measure changes in transmembrane potential or configuration induced by membrane altering agents.

AI Insight

Names and Identifiers

IUPAC Name (2E)-3-propyl-2-[(2E,4E)-5-(3-propyl-1,3-benzothiazol-3-ium-2-yl)penta-2,4-dienylidene]-1,3-benzothiazole;iodide
INCHI InChI=1S/C25H27N2S2.HI/c1-3-18-26-20-12-8-10-14-22(20)28-24(26)16-6-5-7-17-25-27(19-4-2)21-13-9-11-15-23(21)29-25;/h5-17H,3-4,18-19H2,1-2H3;1H/q+1;/p-1
InChi Key GDEURKKLNUGTDA-UHFFFAOYSA-M
Canonical SMILES CCCN1C2=CC=CC=C2SC1=CC=CC=CC3=[N+](C4=CC=CC=C4S3)CCC.[I-]
Isomeric SMILES CCCN\1C2=CC=CC=C2S/C1=C/C=C/C=C/C3=[N+](C4=CC=CC=C4S3)CCC.[I-]
WGK Germany 3
PubChem CID 5706741
Molecular Weight 546.53

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

20 results found

Lot NumberCertificate TypeDateItem
A2507496Certificate of AnalysisDec 26, 2024 D131515
A2507497Certificate of AnalysisDec 26, 2024 D131515
A2507500Certificate of AnalysisDec 26, 2024 D131515
D2219043Certificate of AnalysisFeb 20, 2024 D131515
K2324179Certificate of AnalysisNov 13, 2023 D131515
K2324178Certificate of AnalysisNov 13, 2023 D131515
K2324177Certificate of AnalysisNov 13, 2023 D131515
K2324176Certificate of AnalysisNov 13, 2023 D131515
K2324175Certificate of AnalysisNov 13, 2023 D131515
H2421123Certificate of AnalysisNov 13, 2023 D131515
G2415342Certificate of AnalysisNov 13, 2023 D131515
F2118062Certificate of AnalysisApr 11, 2023 D131515
F2117117Certificate of AnalysisApr 11, 2023 D131515
F1515085Certificate of AnalysisJan 17, 2023 D131515
J2323067Certificate of AnalysisFeb 24, 2022 D131515
D2219052Certificate of AnalysisFeb 24, 2022 D131515
D2219047Certificate of AnalysisFeb 24, 2022 D131515
D2219044Certificate of AnalysisFeb 24, 2022 D131515
D2219034Certificate of AnalysisFeb 24, 2022 D131515
A2310398Certificate of AnalysisFeb 24, 2022 D131515

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Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 3

Related Documents

Reviews

Customer Reviews

Citations of This Product

1. Xue-Yang Wang, Huang-Wei Song, Tian Yi, Ying-Bo Shen, Chong-Shan Dai, Cheng-Tao Sun, De-Jun Liu, Jian-Zhong Shen, Cong-Ming Wu, Yang Wang.  (2023)  Dihydroartemisinin inhibits plasmid transfer in drug-resistant Escherichia coli via limiting energy supply.  ZOOLOGICAL RESEARCH,  44  (5): ( 894–904).  [PMID:37551137] [10.24272/j.issn.2095-8137.2023.084]
2. Miran Tang, Deyi Zhao, Sichen Liu, Xiaotuan Zhang, Zhuocheng Yao, Hule Chen, Cui Zhou, Tieli Zhou, Chunquan Xu.  (2023)  The Properties of Linezolid, Rifampicin, and Vancomycin, as Well as the Mechanism of Action of Pentamidine, Determine Their Synergy against Gram-Negative Bacteria.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,  24  (18): (13812).  [PMID:37762115] [10.3390/ijms241813812]
3. Huangwei Song, Xueyang Wang, Muchen Zhang, Zhiyu Zou, Siyuan Yang, Tian Yi, Jianfeng Wang, Dejun Liu, Yingbo Shen, Chongshan Dai, Zhihai Liu, Timothy R. Walsh, Jianzhong Shen, Congming Wu, Yang Wang.  (2023)  Dual Effects of Feed-Additive-Derived Chelerythrine in Combating Mobile Colistin Resistance.  Engineering,      [PMID:11936845] [10.1016/j.eng.2023.06.012]
4. Yingxin Zhu, Xianzhu Luo, Zihang Yu, Shihui Wen, Guochen Bao, Le Zhang, Cuiling Zhang, Yuezhong Xian.  (2023)  Dye-sensitized rare-earth-doped nanoprobe for simultaneously enhanced NIR-II imaging and precise treatment of bacterial infection.  Acta Biomaterialia,  170  (31): (532).  [PMID:37669712] [10.1016/j.actbio.2023.08.051]
5. Xiang Huang, Chenxin Lu, Wenjie Zhang, Lulu Liu, Zhengbao Zha, Zhaohua Miao.  (2023)  Chiral Sulfur Nanosheets for Dual-Selective Inhibition of Gram-Positive Bacteria.  ACS Nano,  17  (15): (14893–14903).  [PMID:37466081] [10.1021/acsnano.3c03458]
6. Li-Na Chai, Hua Wu, Xue-Jiao Wang, Li-Juan He, Chun-Feng Guo.  (2023)  The Mechanism of Antimicrobial Activity of Conjugated Bile Acids against Lactic Acid Bacilli.  Microorganisms,  11  (7): (1823).  [PMID:37512995] [10.3390/microorganisms11071823]
7. Lizi Yin, Yuhong Gou, Yuyun Dai, Tao Wang, Kexin Gu, Ting Tang, Sajjad Hussain, Xiaoli Huang, Changliang He, Xiaoxia Liang, Gang Shu, Funeng Xu, Ping Ouyang.  (2023)  Cinnamaldehyde Restores Ceftriaxone Susceptibility against Multidrug-Resistant Salmonella.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,  24  (11): (9288).  [PMID:37298240] [10.3390/ijms24119288]
8. Miran Tang, Changrui Qian, Xiaotuan Zhang, Yan Liu, Wei Pan, Zhuocheng Yao, Weiliang Zeng, Chunquan Xu, Tieli Zhou.  (2023)  When Combined with Pentamidine, Originally Ineffective Linezolid Becomes Active in Carbapenem-Resistant Enterobacteriaceae.  Microbiology Spectrum,      [PMID:37125928] [10.1128/spectrum.03138-22]
9. Huan Zeng, Minjing Cheng, Jingyi Liu, Chunxia Hu, Shilin Lin, Ruiqin Cui, Haibo Li, Wencai Ye, Lei Wang, Wei Huang.  (2023)  Pyrimirhodomyrtone inhibits Staphylococcus aureus by affecting the activity of NagA.  BIOCHEMICAL PHARMACOLOGY,  210  (115455).  [PMID:36780990] [10.1016/j.bcp.2023.115455]
10. Wei-Mei Wang, Zhen Zhang, Liang Sun, Chao Ma, Zhi-Hai Liu, Shuai-Cheng Wu.  (2023)  Protective effect of 13-methylberberine against mouse enteritis caused by MRSA.  JOURNAL OF ETHNOPHARMACOLOGY,  304  (115994).  [PMID:36535335] [10.1016/j.jep.2022.115994]
11. Liqiong Sun, Zhijuan Tang, Minxin Wang, Jun Shi, Yajuan Lin, Tiefeng Sun, Zhilu Zou, Zebin Weng.  (2022)  Exploration of Antimicrobial Ingredients in Psoralea corylifolia L. Seed and Related Mechanism against Methicillin-Resistant Staphylococcus aureus.  MOLECULES,  27  (20): (6952).  [PMID:36296544] [10.3390/molecules27206952]
12. Liu Zhi-Hai, Wang Wei-Mei, Zhang Zhen, Sun Liang, Wu Shuai-Cheng.  (2022)  Natural Antibacterial and Antivirulence Alkaloids From Macleaya cordata Against Methicillin-Resistant Staphylococcus aureus.  Frontiers in Pharmacology,  13    [PMID:35370694] [10.3389/fphar.2022.813172]
13. Yuan Liu, Dan Fang, Kangni Yang, Tianqi Xu, Chengrui Su, Ruichao Li, Xia Xiao, Zhiqiang Wang.  (2022)  Sodium dehydroacetate confers broad antibiotic tolerance by remodeling bacterial metabolism.  JOURNAL OF HAZARDOUS MATERIALS,  432  (128645).  [PMID:35299107] [10.1016/j.jhazmat.2022.128645]
14. Chen Yingxian, Zhao Qian, Han Junhua, Lan Xinmiao, Che Jing, Chen Meiwan, Liang Xing-Jie, Ma Xiaowei.  (2022)  Dual Drug Loaded pH-sensitive Micelles for Efficient Bacterial Infection Treatment.  PHARMACEUTICAL RESEARCH,  39  (6): (1165-1180).  [PMID:35165820] [10.1007/s11095-022-03182-5]
15. Xia Xiao, Quanmin Huan, Yanhu Huang, Yuan Liu, Ruichao Li, Xilan Xu, Zhiqiang Wang.  (2022)  Metformin Reverses tmexCD1-toprJ1- and tet(A)-Mediated High-Level Tigecycline Resistance in K. pneumoniae.  Antibiotics-Basel,  11  (2): (162).  [PMID:35203765] [10.3390/antibiotics11020162]
16. Yuqian Jia, Bingqing Yang, Jingru Shi, Dan Fang, Zhiqiang Wang, Yuan Liu.  (2022)  Melatonin prevents conjugative transfer of plasmid-mediated antibiotic resistance genes by disrupting proton motive force.  PHARMACOLOGICAL RESEARCH,  175  (105978).  [PMID:34813930] [10.1016/j.phrs.2021.105978]
17. Jie Meng, Zhengjie Hu, Mengqi He, Jianhua Wang, Xuwei Chen.  (2021)  Gold nanocluster surface ligand exchange: An oxidative stress amplifier for combating multidrug resistance bacterial infection.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,  602  (846).  [PMID:34171749] [10.1016/j.jcis.2021.06.051]
18. Weiwei Zhang, Yueming Wu, Longqiang Liu, Ximian Xiao, Zihao Cong, Ning Shao, Zhongqian Qiao, Kang Chen, Shiqi Liu, Haodong Zhang, Zhemin Ji, Xiaoyan Shao, Yidong Dai, Hongyan He, Jiang Xia, Jian Fei, Runhui Liu.  (2021)  The membrane-targeting mechanism of host defense peptides inspiring the design of polypeptide-conjugated gold nanoparticles exhibiting effective antibacterial activity against methicillin-resistant Staphylococcus aureus.  Journal of Materials Chemistry B,  (25): (5092-5101).  [PMID:34128037] [10.1039/D1TB00533B]
19. Ying Li, Fei Liu, Jiangjiang Zhang, Xiaoye Liu, Peihong Xiao, Haotian Bai, Shang Chen, Dong Wang, Simon H. P. Sung, Ryan T. K. Kwok, Jianzhong Shen, Kui Zhu, Ben Zhong Tang.  (2021)  Efficient Killing of Multidrug-Resistant Internalized Bacteria by AIEgens In Vivo.  Advanced Science,  (9): (2001750).  [PMID:33977040] [10.1002/advs.202001750]
20. Yilun Wang, Huijie Pei, Yuxuan Liu, Xiaohong Huang, Lin Deng, Qinjie Lan, Shujuan Chen, Li He, Aiping Liu, Xiaolin Ao, Shuliang Liu, Likou Zou, Yong Yang.  (2021)  Inhibitory mechanism of cell-free supernatants of Lactobacillus plantarum on Proteus mirabilis and influence of the expression of histamine synthesis-related genes.  FOOD CONTROL,  125  (107982).  [PMID:] [10.1016/j.foodcont.2021.107982]

References

1. Xue-Yang Wang, Huang-Wei Song, Tian Yi, Ying-Bo Shen, Chong-Shan Dai, Cheng-Tao Sun, De-Jun Liu, Jian-Zhong Shen, Cong-Ming Wu, Yang Wang.  (2023)  Dihydroartemisinin inhibits plasmid transfer in drug-resistant Escherichia coli via limiting energy supply.  ZOOLOGICAL RESEARCH,  44  (5): ( 894–904).  [PMID:37551137] [10.24272/j.issn.2095-8137.2023.084]
2. Miran Tang, Deyi Zhao, Sichen Liu, Xiaotuan Zhang, Zhuocheng Yao, Hule Chen, Cui Zhou, Tieli Zhou, Chunquan Xu.  (2023)  The Properties of Linezolid, Rifampicin, and Vancomycin, as Well as the Mechanism of Action of Pentamidine, Determine Their Synergy against Gram-Negative Bacteria.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,  24  (18): (13812).  [PMID:37762115] [10.3390/ijms241813812]
3. Huangwei Song, Xueyang Wang, Muchen Zhang, Zhiyu Zou, Siyuan Yang, Tian Yi, Jianfeng Wang, Dejun Liu, Yingbo Shen, Chongshan Dai, Zhihai Liu, Timothy R. Walsh, Jianzhong Shen, Congming Wu, Yang Wang.  (2023)  Dual Effects of Feed-Additive-Derived Chelerythrine in Combating Mobile Colistin Resistance.  Engineering,      [PMID:11936845] [10.1016/j.eng.2023.06.012]
4. Yingxin Zhu, Xianzhu Luo, Zihang Yu, Shihui Wen, Guochen Bao, Le Zhang, Cuiling Zhang, Yuezhong Xian.  (2023)  Dye-sensitized rare-earth-doped nanoprobe for simultaneously enhanced NIR-II imaging and precise treatment of bacterial infection.  Acta Biomaterialia,  170  (31): (532).  [PMID:37669712] [10.1016/j.actbio.2023.08.051]
5. Xiang Huang, Chenxin Lu, Wenjie Zhang, Lulu Liu, Zhengbao Zha, Zhaohua Miao.  (2023)  Chiral Sulfur Nanosheets for Dual-Selective Inhibition of Gram-Positive Bacteria.  ACS Nano,  17  (15): (14893–14903).  [PMID:37466081] [10.1021/acsnano.3c03458]
6. Li-Na Chai, Hua Wu, Xue-Jiao Wang, Li-Juan He, Chun-Feng Guo.  (2023)  The Mechanism of Antimicrobial Activity of Conjugated Bile Acids against Lactic Acid Bacilli.  Microorganisms,  11  (7): (1823).  [PMID:37512995] [10.3390/microorganisms11071823]
7. Lizi Yin, Yuhong Gou, Yuyun Dai, Tao Wang, Kexin Gu, Ting Tang, Sajjad Hussain, Xiaoli Huang, Changliang He, Xiaoxia Liang, Gang Shu, Funeng Xu, Ping Ouyang.  (2023)  Cinnamaldehyde Restores Ceftriaxone Susceptibility against Multidrug-Resistant Salmonella.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,  24  (11): (9288).  [PMID:37298240] [10.3390/ijms24119288]
8. Miran Tang, Changrui Qian, Xiaotuan Zhang, Yan Liu, Wei Pan, Zhuocheng Yao, Weiliang Zeng, Chunquan Xu, Tieli Zhou.  (2023)  When Combined with Pentamidine, Originally Ineffective Linezolid Becomes Active in Carbapenem-Resistant Enterobacteriaceae.  Microbiology Spectrum,      [PMID:37125928] [10.1128/spectrum.03138-22]
9. Huan Zeng, Minjing Cheng, Jingyi Liu, Chunxia Hu, Shilin Lin, Ruiqin Cui, Haibo Li, Wencai Ye, Lei Wang, Wei Huang.  (2023)  Pyrimirhodomyrtone inhibits Staphylococcus aureus by affecting the activity of NagA.  BIOCHEMICAL PHARMACOLOGY,  210  (115455).  [PMID:36780990] [10.1016/j.bcp.2023.115455]
10. Wei-Mei Wang, Zhen Zhang, Liang Sun, Chao Ma, Zhi-Hai Liu, Shuai-Cheng Wu.  (2023)  Protective effect of 13-methylberberine against mouse enteritis caused by MRSA.  JOURNAL OF ETHNOPHARMACOLOGY,  304  (115994).  [PMID:36535335] [10.1016/j.jep.2022.115994]
11. Liqiong Sun, Zhijuan Tang, Minxin Wang, Jun Shi, Yajuan Lin, Tiefeng Sun, Zhilu Zou, Zebin Weng.  (2022)  Exploration of Antimicrobial Ingredients in Psoralea corylifolia L. Seed and Related Mechanism against Methicillin-Resistant Staphylococcus aureus.  MOLECULES,  27  (20): (6952).  [PMID:36296544] [10.3390/molecules27206952]
12. Liu Zhi-Hai, Wang Wei-Mei, Zhang Zhen, Sun Liang, Wu Shuai-Cheng.  (2022)  Natural Antibacterial and Antivirulence Alkaloids From Macleaya cordata Against Methicillin-Resistant Staphylococcus aureus.  Frontiers in Pharmacology,  13    [PMID:35370694] [10.3389/fphar.2022.813172]
13. Yuan Liu, Dan Fang, Kangni Yang, Tianqi Xu, Chengrui Su, Ruichao Li, Xia Xiao, Zhiqiang Wang.  (2022)  Sodium dehydroacetate confers broad antibiotic tolerance by remodeling bacterial metabolism.  JOURNAL OF HAZARDOUS MATERIALS,  432  (128645).  [PMID:35299107] [10.1016/j.jhazmat.2022.128645]
14. Chen Yingxian, Zhao Qian, Han Junhua, Lan Xinmiao, Che Jing, Chen Meiwan, Liang Xing-Jie, Ma Xiaowei.  (2022)  Dual Drug Loaded pH-sensitive Micelles for Efficient Bacterial Infection Treatment.  PHARMACEUTICAL RESEARCH,  39  (6): (1165-1180).  [PMID:35165820] [10.1007/s11095-022-03182-5]
15. Xia Xiao, Quanmin Huan, Yanhu Huang, Yuan Liu, Ruichao Li, Xilan Xu, Zhiqiang Wang.  (2022)  Metformin Reverses tmexCD1-toprJ1- and tet(A)-Mediated High-Level Tigecycline Resistance in K. pneumoniae.  Antibiotics-Basel,  11  (2): (162).  [PMID:35203765] [10.3390/antibiotics11020162]
16. Yuqian Jia, Bingqing Yang, Jingru Shi, Dan Fang, Zhiqiang Wang, Yuan Liu.  (2022)  Melatonin prevents conjugative transfer of plasmid-mediated antibiotic resistance genes by disrupting proton motive force.  PHARMACOLOGICAL RESEARCH,  175  (105978).  [PMID:34813930] [10.1016/j.phrs.2021.105978]
17. Jie Meng, Zhengjie Hu, Mengqi He, Jianhua Wang, Xuwei Chen.  (2021)  Gold nanocluster surface ligand exchange: An oxidative stress amplifier for combating multidrug resistance bacterial infection.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,  602  (846).  [PMID:34171749] [10.1016/j.jcis.2021.06.051]
18. Weiwei Zhang, Yueming Wu, Longqiang Liu, Ximian Xiao, Zihao Cong, Ning Shao, Zhongqian Qiao, Kang Chen, Shiqi Liu, Haodong Zhang, Zhemin Ji, Xiaoyan Shao, Yidong Dai, Hongyan He, Jiang Xia, Jian Fei, Runhui Liu.  (2021)  The membrane-targeting mechanism of host defense peptides inspiring the design of polypeptide-conjugated gold nanoparticles exhibiting effective antibacterial activity against methicillin-resistant Staphylococcus aureus.  Journal of Materials Chemistry B,  (25): (5092-5101).  [PMID:34128037] [10.1039/D1TB00533B]
19. Ying Li, Fei Liu, Jiangjiang Zhang, Xiaoye Liu, Peihong Xiao, Haotian Bai, Shang Chen, Dong Wang, Simon H. P. Sung, Ryan T. K. Kwok, Jianzhong Shen, Kui Zhu, Ben Zhong Tang.  (2021)  Efficient Killing of Multidrug-Resistant Internalized Bacteria by AIEgens In Vivo.  Advanced Science,  (9): (2001750).  [PMID:33977040] [10.1002/advs.202001750]
20. Yilun Wang, Huijie Pei, Yuxuan Liu, Xiaohong Huang, Lin Deng, Qinjie Lan, Shujuan Chen, Li He, Aiping Liu, Xiaolin Ao, Shuliang Liu, Likou Zou, Yong Yang.  (2021)  Inhibitory mechanism of cell-free supernatants of Lactobacillus plantarum on Proteus mirabilis and influence of the expression of histamine synthesis-related genes.  FOOD CONTROL,  125  (107982).  [PMID:] [10.1016/j.foodcont.2021.107982]

Solution Calculators