Determine the necessary mass, volume, or concentration for preparing a solution.
Basic Description
| Synonyms | I-BCP | 1,3-Chbp | NSC 9183 | 1-Bromo-3-chloropropane [UN2688] [Poison] | 3-Chloro-1-bromo propane | A802077 | Q22829220 | 1-BROMO-3-CHLOROPROPANE [HSDB] | 1-bromo-3-chlorpropane | F0001-0201 | 3-chloro-1- bromopropane | 4-01-00-00212 (Beilstein Handbook |
|---|---|
| Specifications & Purity | ≥99% |
| Storage Temp | Protected from light,Room temperature |
| Shipped In | Normal |
| Product Description | 1-Bromo-3-chloropropane is a solvent that has been described as a less toxic replacement for chloroform in the liquid-phase separation and isolation of RNA from DNA and proteins. 1-Bromo-3-chloropropane is described to be efficacious in the single-step isolation of RNA from rat liver and various tissues, human placenta and human MCF-7 cells, and from bean and corn sprout plant material. No significant difference in RNA recovery was observed between chloroform and 1-Bromo-3-chloropropane as solvents in this process. |
AI Insight
Mechanisms of Action
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Names and Identifiers
| Pubchem Sid | 488180648 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488180648 |
| IUPAC Name | 1-bromo-3-chloropropane |
| INCHI | InChI=1S/C3H6BrCl/c4-2-1-3-5/h1-3H2 |
| InChi Key | MFESCIUQSIBMSM-UHFFFAOYSA-N |
| Canonical SMILES | C(CCl)CBr |
| Isomeric SMILES | C(CCl)CBr |
| WGK Germany | 2 |
| RTECS | TX4113000 |
| PubChem CID | 8006 |
| UN Number | 2688 |
| Packing Group | III |
| Molecular Weight | 157.44 |
| Beilstein | 605278 |
| Reaxy-Rn | 605278 |
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 E2327191 | Certificate of Analysis | Mar 03, 2025 | B105780 |
| E2327182 | Certificate of Analysis | Mar 03, 2025 | B105780 |
| E2327181 | Certificate of Analysis | Mar 03, 2025 | B105780 |
| L2413484 | Certificate of Analysis | Dec 07, 2024 | B105780 |
| L2413452 | Certificate of Analysis | Dec 07, 2024 | B105780 |
| L2413430 | Certificate of Analysis | Dec 07, 2024 | B105780 |
| J2418488 | Certificate of Analysis | Oct 12, 2024 | B105780 |
| J2418447 | Certificate of Analysis | Oct 12, 2024 | B105780 |
| L2210179 | Certificate of Analysis | Sep 19, 2024 | B105780 |
| L2210174 | Certificate of Analysis | Sep 19, 2024 | B105780 |
| L2210170 | Certificate of Analysis | Sep 19, 2024 | B105780 |
| L2210165 | Certificate of Analysis | Sep 19, 2024 | B105780 |
| L2210147 | Certificate of Analysis | Sep 19, 2024 | B105780 |
| H2224050 | Certificate of Analysis | May 07, 2024 | B105780 |
| H2224055 | Certificate of Analysis | May 07, 2024 | B105780 |
| H2224054 | Certificate of Analysis | May 07, 2024 | B105780 |
| D2408156 | Certificate of Analysis | Mar 30, 2024 | B105780 |
| D2408155 | Certificate of Analysis | Mar 30, 2024 | B105780 |
| C2429154 | Certificate of Analysis | Mar 15, 2024 | B105780 |
| C2429155 | Certificate of Analysis | Mar 15, 2024 | B105780 |
| C2429151 | Certificate of Analysis | Mar 15, 2024 | B105780 |
| C2429158 | Certificate of Analysis | Mar 15, 2024 | B105780 |
| E2202027 | Certificate of Analysis | Feb 06, 2024 | B105780 |
| B2418107 | Certificate of Analysis | Jan 27, 2024 | B105780 |
| A2218227 | Certificate of Analysis | Oct 16, 2023 | B105780 |
| A2218229 | Certificate of Analysis | Oct 16, 2023 | B105780 |
| A2218230 | Certificate of Analysis | Oct 16, 2023 | B105780 |
| A2218231 | Certificate of Analysis | Oct 16, 2023 | B105780 |
| I2313061 | Certificate of Analysis | Aug 24, 2023 | B105780 |
| I2313115 | Certificate of Analysis | Aug 24, 2023 | B105780 |
| I2313116 | Certificate of Analysis | Aug 24, 2023 | B105780 |
| K2103651 | Certificate of Analysis | Aug 22, 2023 | B105780 |
| E2327187 | Certificate of Analysis | May 15, 2023 | B105780 |
| E2327183 | Certificate of Analysis | May 15, 2023 | B105780 |
| F2130063 | Certificate of Analysis | Apr 12, 2023 | B105780 |
| B2301272 | Certificate of Analysis | Feb 09, 2023 | B105780 |
| L2210157 | Certificate of Analysis | Nov 30, 2022 | B105780 |
| L2210164 | Certificate of Analysis | Nov 30, 2022 | B105780 |
| L2210153 | Certificate of Analysis | Nov 30, 2022 | B105780 |
| L2010166 | Certificate of Analysis | Sep 21, 2022 | B105780 |
| H2224056 | Certificate of Analysis | Aug 04, 2022 | B105780 |
| E2202047 | Certificate of Analysis | Mar 22, 2022 | B105780 |
| A2218228 | Certificate of Analysis | Jan 03, 2022 | B105780 |
| A2218226 | Certificate of Analysis | Jan 03, 2022 | B105780 |
Show more⌵
Safety and Hazards(GHS)
| Pictogram(s) | GHS06, GHS08 |
|---|---|
| Signal | Danger |
| Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H331:Toxic if inhaled H341:Suspected of causing genetic defects H412:Harmful to aquatic life with long lasting effects H302:Harmful if swallowed H226:Flammable liquid and vapor H332:Harmful if inhaled |
| Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P370+P378:In case of fire: Use ... to extinguish. P210:Keep away from heat, hot surface, sparks, open flames and other ignition sources. - No smoking. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P264:Wash hands [and …] thoroughly after handling. P403+P235:Store in a well-ventilated place. Keep cool. P303+P361+P353:IF ON SKIN (or hair): Take off Immediately all contaminated clothing. Rinse SKIN with water [or shower]. P281:Use personal protective equipment as required. P271:Use only outdoors or in a well-ventilated area. P241:Use explosion-proof [electrical/ventilating/lighting/.../] equipment. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P242:Use only non-sparking tools. P243:Take precautionary measures against static discharge. P203:Obtain, read and follow all safety instructions before use. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P318:if exposed or concerned, get medical advice. P317:Get emergency medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P316:Get emergency medical help immediately. P319:Get medical help if you feel unwell. |
| WGK Germany | 2 |
| RTECS | TX4113000 |
| Reaxy-Rn | 605278 |
| Class | 6.1 |
Related Documents
Reviews
Customer Reviews
Citations of This Product
| 1. Wei-Min Chen, Juan-Juan Shao, Yi Zhang, Zhen-Dong Xue, Peng-lai Liu, Jian-ling Ni, Fang-Ming Wang. (2023) Effects of different metal centers on the structure and luminescence properties of hybrid materials. JOURNAL OF SOLID STATE CHEMISTRY, 328 (124356). [PMID:24026640] [10.1016/j.jssc.2023.124356] |
| 2. Yun-Chun Zhao, Hai-Li Zheng, Xiao-Rong Wang, Xiao-Ling Zheng, Yue Chen, Wei-Dong Fei, Yong-Quan Zheng, Wen-Xi Wang, Cai-Hong Zheng. (2020) Enhanced Percutaneous Delivery of Methotrexate Using Micelles Prepared with Novel Cationic Amphipathic Material. International Journal of Nanomedicine, [PMID:32547012] [10.2147/IJN.S251431] |
References
| 1. Sabogal-Guáqueta AM et al.. (2019) Linalool attenuates oxidative stress and mitochondrial dysfunction mediated by glutamate and NMDA toxicity.. Biomed Pharmacother, 118 (109295). [PMID:31545255] |
| 2. L V Kuznetsova,S P Nogina. (1994-01-01) [Gas chromatography in the evaluation of 1,3-chlorobromopropane in the air of populated areas].. Gigiena i sanitariia, ((1)): (40-40). [PMID:8168709] |
| 3. Tae Hwan Park,Dong Kyun Rah,Yosep Chong,June-kyu Kim. (2013-07-03) The effects of botulinum toxin A on survival of rat TRAM flap with vertical midline scar.. Annals of plastic surgery, 74 ((1)): (100-106). [PMID:23817458] |
| 4. Michelle L Thompson,Pan Chen,Xiaohui Yan,Hanna Kim,Akeem R Borom,Nathan B Roberts,Kim A Caldwell,Guy A Caldwell. (2013-12-07) TorsinA rescues ER-associated stress and locomotive defects in C. elegans models of ALS.. Disease models & mechanisms, 7 ((2)): (233-243). [PMID:24311730] |
| 5. Niels Schlichting,Tilo Dehne,Karsten Mans,Michaela Endres,Bruno Stuhlmüller,Michael Sittinger,Christian Kaps,Jochen Ringe. (2014-03-19) Suitability of porcine chondrocyte micromass culture to model osteoarthritis in vitro.. Molecular pharmaceutics, 11 ((7)): (2092-2105). [PMID:24635637] |
| 6. Longyan Liao,Jenny Liu,Erik C Dreaden,Stephen W Morton,Kevin E Shopsowitz,Paula T Hammond,Jeremiah A Johnson. (2014-04-15) A convergent synthetic platform for single-nanoparticle combination cancer therapy: ratiometric loading and controlled release of cisplatin, doxorubicin, and camptothecin.. Journal of the American Chemical Society, 136 ((16)): (5896-5899). [PMID:24724706] |
| 7. Penghua Yang,Aihua Dai,Andrei P Alexenko,Yajun Liu,Amanda J Stephens,Laura C Schulz,Danny J Schust,R Michael Roberts,Toshihiko Ezashi. (2014-07-25) Abnormal oxidative stress responses in fibroblasts from preeclampsia infants.. PloS one, 9 ((7)): (e103110-e103110). [PMID:25058409] |
| 8. Tien D Ho,Peter M Yehl,Nik P Chetwyn,Jin Wang,Jared L Anderson,Qiqing Zhong. (2014-08-26) Determination of trace level genotoxic impurities in small molecule drug substances using conventional headspace gas chromatography with contemporary ionic liquid diluents and electron capture detection.. Journal of chromatography. A, 1361 (217-228). [PMID:25151038] |
| 9. Siroj Jitprasutwit,Catherine Ong,Niramol Juntawieng,Wen Fong Ooi,Claudia M Hemsley,Paiboon Vattanaviboon,Richard W Titball,Patrick Tan,Sunee Korbsrisate. (2014-09-13) Transcriptional profiles of Burkholderia pseudomallei reveal the direct and indirect roles of Sigma E under oxidative stress conditions.. BMC genomics, 15 (787-787). [PMID:25214426] |
| 10. Arpita Ray,Siyuan Zhang,Courtney Rentas,Kim A Caldwell,Guy A Caldwell. (2014-11-28) RTCB-1 mediates neuroprotection via XBP-1 mRNA splicing in the unfolded protein response pathway.. The Journal of neuroscience : the official journal of the Society for Neuroscience, 34 ((48)): (16076-16085). [PMID:25429148] |
| 11. Gary R McCoy,Nicolas Touzet,Gerard T A Fleming,Robin Raine. (2015-01-30) Evolution of the MIDTAL microarray: the adaption and testing of oligonucleotide 18S and 28S rDNA probes and evaluation of subsequent microarray generations with Prymnesium spp. cultures and field samples.. Environmental science and pollution research international, 22 ((13)): (9704-9716). [PMID:25631743] |
| 12. Agnieszka Rak,Eliza Drwal,Anna Karpeta,Ewa Ł Gregoraszczuk. (2015-05-01) Regulatory Role of Gonadotropins and Local Factors Produced by Ovarian Follicles on In Vitro Resistin Expression and Action on Porcine Follicular Steroidogenesis.. Biology of reproduction, 92 ((6)): (142-142). [PMID:25926437] |
| 13. T Hideshima,F Cottini,H Ohguchi,J Jakubikova,G Gorgun,N Mimura,Y-T Tai,N C Munshi,P G Richardson,K C Anderson. (2015-05-16) Rational combination treatment with histone deacetylase inhibitors and immunomodulatory drugs in multiple myeloma.. Blood cancer journal, 5 (e312-e312). [PMID:25978432] |
| 14. Luwanika Mlera,Danielle K Offerdahl,Craig Martens,Stephen F Porcella,Wessam Melik,Marshall E Bloom. (2015-06-06) Development of a Model System for Tick-Borne Flavivirus Persistence in HEK 293T Cells.. mBio, 6 ((3)): (e00614-e00614). [PMID:26045539] |
| 15. Mithila Vaidya,Diana Lehner,Stephan Handschuh,Freya F Jay,Reinhold G Erben,Marlon R Schneider. (2015-06-24) Osteoblast-specific overexpression of amphiregulin leads to transient increase in femoral cancellous bone mass in mice.. Bone, 81 (36-46). [PMID:26103093] |
| 16. Melissa G Castillo-Lizardo,Isabel M Aragón,Vivian Carvajal,Isabel M Matas,María Luisa Pérez-Bueno,María-Trinidad Gallegos,Matilde Barón,Cayo Ramos. (2015-08-20) Contribution of the non-effector members of the HrpL regulon, iaaL and matE, to the virulence of Pseudomonas syringae pv. tomato DC3000 in tomato plants.. BMC microbiology, 15 (165-165). [PMID:26285820] |
| 17. Kelly M Mabry,Samuel Z Payne,Kristi S Anseth. (2015-10-05) Microarray analyses to quantify advantages of 2D and 3D hydrogel culture systems in maintaining the native valvular interstitial cell phenotype.. Biomaterials, 74 (31-41). [PMID:26433490] |
| 18. Rosa Fernández,Robert J Kallal,Dimitar Dimitrov,Jesús A Ballesteros,Miquel A Arnedo,Gonzalo Giribet,Gustavo Hormiga. (2018-05-01) Phylogenomics, Diversification Dynamics, and Comparative Transcriptomics across the Spider Tree of Life.. Current biology : CB, 28 ((9)): (1489-1497). [PMID:29706520] |
| 19. Rositsa Dueva,Karen Akopyan,Chiara Pederiva,Davide Trevisan,Soniya Dhanjal,Arne Lindqvist,Marianne Farnebo. (2019-08-27) Neutralization of the Positive Charges on Histone Tails by RNA Promotes an Open Chromatin Structure.. Cell chemical biology, 26 ((10)): (1436-1449). [PMID:31447351] |
| 20. Eric G Meissner,David Wu,Anu Osinusi,Dimitra Bon,Kimmo Virtaneva,Dan Sturdevant,Steve Porcella,Honghui Wang,Eva Herrmann,John McHutchison,Anthony F Suffredini,Michael Polis,Stephen Hewitt,Ludmila Prokunina-Olsson,Henry Masur,Anthony S Fauci,Shyamasundaran Kottilil. (2014-07-02) Endogenous intrahepatic IFNs and association with IFN-free HCV treatment outcome.. The Journal of clinical investigation, 124 ((8)): (3352-3363). [PMID:24983321] |
| 21. Morten Frier Gjerstorff,Mette Marie Relster,Katrine Buch Viden Greve,Jesper Bonnet Moeller,Daniel Elias,Jonas Nørrelund Lindgreen,Steffen Schmidt,Jan Mollenhauer,Bjørn Voldborg,Christina Bøg Pedersen,Nadine Heidi Brückmann,Niels Erik Møllegaard,Henrik Jørn Ditzel. (2014-09-25) SSX2 is a novel DNA-binding protein that antagonizes polycomb group body formation and gene repression.. Nucleic acids research, 42 ((18)): (11433-11446). [PMID:25249625] |
| 22. John Bowes,Ashley Budu-Aggrey,Ulrike Huffmeier,Steffen Uebe,Kathryn Steel,Harry L Hebert,Chris Wallace,Jonathan Massey,Ian N Bruce,James Bluett,Marie Feletar,Ann W Morgan,Helena Marzo-Ortega,Gary Donohoe,Derek W Morris,Philip Helliwell,Anthony W Ryan,David Kane,Richard B Warren,Eleanor Korendowych,Gerd-Marie Alenius,Emiliano Giardina,Jonathan Packham,Ross McManus,Oliver FitzGerald,Neil McHugh,Matthew A Brown,Pauline Ho,Frank Behrens,Harald Burkhardt,Andre Reis,Anne Barton. (2015-02-06) Dense genotyping of immune-related susceptibility loci reveals new insights into the genetics of psoriatic arthritis.. Nature communications, 6 (6046-6046). [PMID:25651891] |
| 23. Michael J Wourms,Courtney E W Sulentic. (2015-03-10) The aryl hydrocarbon receptor regulates an essential transcriptional element in the immunoglobulin heavy chain gene.. Cellular immunology, 295 ((1)): (60-66). [PMID:25749007] |
| 24. Philippe Haouzi,Andry Van de Louw. (2015-04-26) Persistent reduced oxygen requirement following blood transfusion during recovery from hemorrhagic shock.. Respiratory physiology & neurobiology, 215 (39-46). [PMID:25911557] |
| 25. Beatriz Álvarez,Kasper Krogh-Andersen,Christian Tellgren-Roth,Noelia Martínez,Gökçe Günaydın,Yin Lin,M Cruz Martín,Miguel A Álvarez,Lennart Hammarström,Harold Marcotte. (2015-06-21) An Exopolysaccharide-Deficient Mutant of Lactobacillus rhamnosus GG Efficiently Displays a Protective Llama Antibody Fragment against Rotavirus on Its Surface.. Applied and environmental microbiology, 81 ((17)): (5784-5793). [PMID:26092449] |
| 26. Elaine S Coimbra,Luciana M R Antinarelli,Natália P Silva,Isabela O Souza,Raissa S Meinel,Marcele N Rocha,Rodrigo P P Soares,Adilson D da Silva. (2016-10-30) Quinoline derivatives: Synthesis, leishmanicidal activity and involvement of mitochondrial oxidative stress as mechanism of action.. Chemico-biological interactions, 260 (50-57). [PMID:27789199] |
| 27. John-Poul Ng-Blichfeldt,Anneke Schrik,Rosa K Kortekaas,Jacobien A Noordhoek,Irene H Heijink,Pieter S Hiemstra,Jan Stolk,Melanie Königshoff,Reinoud Gosens. (2018-09-22) Retinoic acid signaling balances adult distal lung epithelial progenitor cell growth and differentiation.. EBioMedicine, 36 (461-474). [PMID:30236449] |
| 28. John Kerwin,Israr Khan,Elizabeth Iorns,Rachel Tsui,Alexandria Denis,Nicole Perfito,Timothy M Errington. (2020-04-22) Replication Study: A coding-independent function of gene and pseudogene mRNAs regulates tumour biology.. eLife, 9 [PMID:32314732] |
| 29. Wei-Min Chen, Juan-Juan Shao, Yi Zhang, Zhen-Dong Xue, Peng-lai Liu, Jian-ling Ni, Fang-Ming Wang. (2023) Effects of different metal centers on the structure and luminescence properties of hybrid materials. JOURNAL OF SOLID STATE CHEMISTRY, 328 (124356). [PMID:24026640] [10.1016/j.jssc.2023.124356] |
| 30. Yun-Chun Zhao, Hai-Li Zheng, Xiao-Rong Wang, Xiao-Ling Zheng, Yue Chen, Wei-Dong Fei, Yong-Quan Zheng, Wen-Xi Wang, Cai-Hong Zheng. (2020) Enhanced Percutaneous Delivery of Methotrexate Using Micelles Prepared with Novel Cationic Amphipathic Material. International Journal of Nanomedicine, [PMID:32547012] [10.2147/IJN.S251431] |