| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| D155634-50mg | 50mg | 3 | $58.90 | |
| D155634-250mg | 250mg | 3 | $241.90 | |
| D155634-1g | 1g | 3 | $871.90 |
| Synonyms | CS-0042337 | GPEtn(18:1w9/18:1w9) | 1,2-Dioleoyl-sn-gl | AMY10805 | DOPE, l- | SCHEMBL25038 | Ethanol, 2-amino-, dihydrogen phosphate (ester), monoester with 1,2-diolein, L- | 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine | AS-74734 | PE(18:1/18:1) | 1,2- |
|---|---|
| Specifications & Purity | ≥98% |
| Biochemical and Physiological Mechanisms | It has been found that DOPE in the mixed film reduces the fluorescence lifetime and increases the acyl chain sequence. DOPE is an important component of cationic liposomes, specifically designed to deliver DNA to glioblastoma and kidney cell lines (gene t |
| Storage Temp | Store at -20°C,Argon charged |
| Shipped In | Ice chest + Ice pads |
| Product Description | Application DOPE in mixed membranes have been found to decrease fluorescence lifetime and increase acyl-chain order. DOPE is an essential component of cationic liposomes designed to deliver DNA into gliosarcoma and kidney cell lines (gene therapy). |
| Pubchem Sid | 504764803 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504764803 |
| IUPAC Name | [(2R)-3-[2-aminoethoxy(hydroxy)phosphoryl]oxy-2-[(Z)-octadec-9-enoyl]oxypropyl] (Z)-octadec-9-enoate |
| INCHI | InChI=1S/C41H78NO8P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(43)47-37-39(38-49-51(45,46)48-36-35-42)50-41(44)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h17-20,39H,3-16,21-38,42H2,1-2H3,(H,45,46)/b19-17-,20-18-/t39-/m1/s1 |
| InChi Key | MWRBNPKJOOWZPW-NYVOMTAGSA-N |
| Canonical SMILES | CCCCCCCCC=CCCCCCCCC(=O)OCC(COP(=O)(O)OCCN)OC(=O)CCCCCCCC=CCCCCCCCC |
| Isomeric SMILES | CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@H](COP(=O)(O)OCCN)OC(=O)CCCCCCC/C=C\CCCCCCCC |
| PubChem CID | 9546757 |
| Molecular Weight | 744.05 |
| Reaxy-Rn | 1718431 |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 K2411419 | Certificate of Analysis | Oct 11, 2024 | D155634 |
| K2411420 | Certificate of Analysis | Oct 11, 2024 | D155634 |
| G2312562 | Certificate of Analysis | Dec 28, 2022 | D155634 |
| G2312622 | Certificate of Analysis | Dec 28, 2022 | D155634 |
| G2312628 | Certificate of Analysis | Dec 28, 2022 | D155634 |
| G2312674 | Certificate of Analysis | Dec 28, 2022 | D155634 |
| G2312680 | Certificate of Analysis | Dec 28, 2022 | D155634 |
| G2312686 | Certificate of Analysis | Dec 28, 2022 | D155634 |
| J2418149 | Certificate of Analysis | Dec 28, 2022 | D155634 |
| I2202202 | Certificate of Analysis | Aug 09, 2022 | D155634 |
| I2202203 | Certificate of Analysis | Aug 09, 2022 | D155634 |
| I2202205 | Certificate of Analysis | Aug 09, 2022 | D155634 |
| C2228166 | Certificate of Analysis | Mar 08, 2022 | D155634 |
| C2228167 | Certificate of Analysis | Mar 08, 2022 | D155634 |
| C2228187 | Certificate of Analysis | Mar 08, 2022 | D155634 |
| Reaxy-Rn | 1718431 |
|---|
Starting at $1,062.90
| 1. Hui-Zhen Yang, Yue Hu, Jia-Jia Chen, Rui-Mo Zhao, Lin Pu, Xiao-Qi Yu, Ji Zhang. (2024) Nitric oxide/PDT combination therapy by the fluorescent self-reporting Co-delivery platforms. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, 92 (105296). [PMID:] [10.1016/j.jddst.2023.105296] |
| 2. Di Chuan, Rangrang Fan, Bo Chen, Yangmei Ren, Min Mu, Haifeng Chen, Bingwen Zou, Haohao Dong, Aiping Tong, Gang Guo. (2023) Lipid–Polymer Hybrid Nanoparticles with Both PD-L1 Knockdown and Mild Photothermal Effect for Tumor Photothermal Immunotherapy. ACS Applied Materials & Interfaces, [PMID:37605506] [10.1021/acsami.3c07648] |
| 3. Run Han, Zhuyifan Ye, Yunsen Zhang, Yaxin Cheng, Ying Zheng, Defang Ouyang. (2023) Predicting liposome formulations by the integrated machine learning and molecular modeling approaches. Asian Journal of Pharmaceutical Sciences, 18 (100811). [PMID:37274923] [10.1016/j.ajps.2023.100811] |
| 4. Xiu Han, Yan Lu, Zhaoluo Xu, Yanan Chu, Xueping Ma, Haiping Wu, Bingjie Zou, Guohua Zhou. (2023) Anionic liposomes prepared without organic solvents for effective siRNA delivery. IET Nanobiotechnology, [PMID:36786285] [10.1049/nbt2.12117] |
| 1. Hui-Zhen Yang, Yue Hu, Jia-Jia Chen, Rui-Mo Zhao, Lin Pu, Xiao-Qi Yu, Ji Zhang. (2024) Nitric oxide/PDT combination therapy by the fluorescent self-reporting Co-delivery platforms. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, 92 (105296). [PMID:] [10.1016/j.jddst.2023.105296] |
| 2. Di Chuan, Rangrang Fan, Bo Chen, Yangmei Ren, Min Mu, Haifeng Chen, Bingwen Zou, Haohao Dong, Aiping Tong, Gang Guo. (2023) Lipid–Polymer Hybrid Nanoparticles with Both PD-L1 Knockdown and Mild Photothermal Effect for Tumor Photothermal Immunotherapy. ACS Applied Materials & Interfaces, [PMID:37605506] [10.1021/acsami.3c07648] |
| 3. Run Han, Zhuyifan Ye, Yunsen Zhang, Yaxin Cheng, Ying Zheng, Defang Ouyang. (2023) Predicting liposome formulations by the integrated machine learning and molecular modeling approaches. Asian Journal of Pharmaceutical Sciences, 18 (100811). [PMID:37274923] [10.1016/j.ajps.2023.100811] |
| 4. Xiu Han, Yan Lu, Zhaoluo Xu, Yanan Chu, Xueping Ma, Haiping Wu, Bingjie Zou, Guohua Zhou. (2023) Anionic liposomes prepared without organic solvents for effective siRNA delivery. IET Nanobiotechnology, [PMID:36786285] [10.1049/nbt2.12117] |
